June 15, 2010

Biomedical sciences professor receives $1.5 million grant

Award will further Dr. John Mantsch’s research into drug abuse

MILWAUKEE – Dr. John Mantsch, associate professor and chair of biomedical sciences in Marquette University’s College of Health Sciences, has been awarded a five-year, $1.5 million grant renewal from the National Institutes of Health for his research on cocaine addiction.

The grant provides critical support of a research project Mantsch started in 2002, which examines the neuropathways through which susceptibility to drug relapse during periods of stress is heightened in cocaine addiction.

“For many cocaine addicts, drug use is a stress-driven behavior,” Mantsch said. “The goal of this research program is to identify not just why, but also how stress can trigger relapse among cocaine addicts.”

This is the second grant of more than $1 million Mantsch has received within the past 12 months for the study of cocaine addiction. In July 2009 he and Drs. David Baker and Douglas Lobner, two other associate professors in the College of Health Sciences, received a two-year, $1.4 million grant from the National Institutes of Health to study and develop novel compounds for the treatment of cocaine addiction.

“Dr. Mantsch’s important work is pivotal in addressing a serious public health concern,” said Dr. William Cullinan, dean of the College of Health Sciences. “That this grant has been renewed represents an acknowledgment of Dr. Mantsch’s previous research successes and a desire to move his work forward.”

The College of Health Sciences is home to the university’s Integrative Neuroscience Research Center, a multidisciplinary center that includes more than 30 faculty members who all are actively engaged in research projects aimed at understanding the brain’s stress and reward circuitries, having important implications for mood and cognitive disorders and addiction.

Media interested in interviewing Mantsch should contact Christopher Stolarski at (414) 288-1988 or christopher.stolarski@marquette.edu.

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