Campus

GENERAL INFORMATION

FOR RESEARCHERS

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Experiments that are Exempt from the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules (NIH Guidelines)

1. Are there experiments that are exempt from the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules?

 

 

Genetically Modified (Transgenic) Animals and the Use of Recombinant or Synthetic Nucleic Acid Molecules in Animals

1. Under which section of the NIH Guidelines does the generation of transgenic rodents fall?

2. Would the breeding of two different lines of knock-out mice require IBC approval under the NIH Guidelines?

3. Is IBC registration and approval needed for the maintenance of a transgenic animal colony?

4. Is the purchase and transfer of transgenic rodents exempt from NIH Guidelines?

5. Are gene ablation studies covered by the NIH Guidelines?

6. Who has the responsibility to review the generation of transfenic animals if Marquette is generating animals for investigators who are not affiliated with Marquette?

7. When existing transgenic animals at Marquette are purchased or transferred to an investigator outside of Marquette, who should review and approve the use of these animals?

1. Under which section of the NIH Guidelines does the generation of transgenic rodents fall? - The creation of transgenci rodents falls under one of two section of the NIH Guidelines depending on the containment level required to house the rodents. Experiments involving the creation of transgenic rodents that can be housed under Biosafety Level 1 conditions are covered under Section III-E-3. Experiments involving the generation of transgenic rodents requiring BL2 containment are covered under Section III-D-4. back to list

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National Instituties of Health - Office of Science Policy (OSP)

What is the Office of Science Policy and what do they do? - OSP promotes science, safety and ethics in the development of public p[olicies in three areas: Biomedical Technology Assessment, Biosafety, and Biosecurity. By monitoring research and through consultation, coordination, and analysis, the office develops policies related to:

Specific activities include optimizing the conduct and oversight of gene transfer research, updating and interpreting biosafety policies under the NIH Guidelines Involving Research with Recombinant and Synthetic Nucleic Acids, providing criticial input on Governmental policies regarding dual use research, the NIH Stem Cell Registry.

 

 

 

 

 


SITE MENU

Schroeder Complex

Mission Statement

The mission of the Office of Research Compliance, in cooperation with and in support of the Institutional Review Board, Institutional Animal Care and Use Committee, Radiation Safety Committee, and Institutional Biosafety Committee, is to facilitate safe and ethical research conducted by Marquette faculty, staff and students in the areas of human subjects, animal subjects, radiation safety and biosafety.