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$1.45 million grant from NIH to Antony Lab

The Antony lab has received a four-year $1.45 million grant from the National Institutes of Health to investigate the function of proteins involved in DNA repair and recombination. The project seeks to understand the mechanism of action of Replication Protein A (RPA), a key player in maintaining the integrity of the genome. Defects in RPA and coordination of DNA repair leads to genomic instabilities, a hallmark of most cancers.

Drs. Antony, St. Maurice, Petrella, Manogaran, and Yang receive the NSF-MRI grant of $251,424 for acquisition of a Total Internal Reflection Fluorescence (TIRF) Microscope for Research and Education at Marquette University and the Greater Milwaukee Region for single molecule studies.

Dr. Sofia Origanti’s lab recently uncovered a new mechanism of regulation of the eukaryotic initiation factor-6 in response to starvation-induced stress. She received a research grant of $457,000 from the NIH through the NIGMS-R15 funding mechanism for this project. Read more